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Edwards' syndrome affects about 3 out of every 10,000 births.Babies affected by Patau's syndrome can have heart problems, a cleft lip and palate, growth problems, poorly formed eyes and ears, problems with their kidneys, and be unable to stand or walk.Chromosomes carry the genes that determine how we develop. Problems can occur when sperm or egg cells are produced, which can lead to a baby having an extra chromosome. In Down's syndrome, there is an extra copy of chromosome 21 in each cell.A baby born with Down's syndrome will have a learning disability.A screening test for Down's, Edwards' and Patau's syndromes is available from weeks 10-14 of pregnancy.It is called the combined test because it combines an ultrasound scan with a blood test.

All babies born with Edwards' or Patau's syndromes will have a wide range of problems, which are usually very serious. Babies affected by Edwards' syndrome can have heart problems, unusual head and facial features, growth problems, and be unable to stand or walk.

In Patau's syndrome, there is an extra copy of chromosome 13 in each cell.

Sadly, most babies with Edwards' or Patau's syndromes will die before they are born or die shortly after birth.

For Down’s syndrome, a blood test called the quadruple test is available from weeks 14-20 of pregnancy.

For Patau’s and Edwards’ syndromes, you will be offered a mid-pregnancy scan that checks for physical abnormalities.